<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:fbe07dfa-ed1e-454d-8aa4-2386b0f2fa8c,g:90669cd9-c928-482c-8d7a-98da75425495-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.upstartholdings.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="upst-20250930.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_cead4f0c-f176-4efe-adcf-8faa0d7c9276" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_15ec062b-6672-457c-838f-1f91ebafa0d5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_cead4f0c-f176-4efe-adcf-8faa0d7c9276" xlink:to="loc_us-gaap_CommonStockValue_15ec062b-6672-457c-838f-1f91ebafa0d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_241ef45b-ad48-415b-a0d1-c1a7ca53ac80" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_cead4f0c-f176-4efe-adcf-8faa0d7c9276" xlink:to="loc_us-gaap_AdditionalPaidInCapital_241ef45b-ad48-415b-a0d1-c1a7ca53ac80" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_78dc8996-4657-4bd7-b607-a24cf7525f02" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_cead4f0c-f176-4efe-adcf-8faa0d7c9276" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_78dc8996-4657-4bd7-b607-a24cf7525f02" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_99fe34ad-6336-473d-b9b3-30562777c083" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_6a45c321-2836-4de7-abbe-13df8accf276" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_99fe34ad-6336-473d-b9b3-30562777c083" xlink:to="loc_us-gaap_Liabilities_6a45c321-2836-4de7-abbe-13df8accf276" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_770d20ef-826f-47c9-829c-3b4c3bfddea9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_99fe34ad-6336-473d-b9b3-30562777c083" xlink:to="loc_us-gaap_StockholdersEquity_770d20ef-826f-47c9-829c-3b4c3bfddea9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_f9aca056-4649-4d17-b19b-b941dea6cb2c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_99fe34ad-6336-473d-b9b3-30562777c083" xlink:to="loc_us-gaap_CommitmentsAndContingencies_f9aca056-4649-4d17-b19b-b941dea6cb2c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCash_e6ac4bb6-f4cf-4431-b9ae-f357757317cd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCash"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_RestrictedCash_e6ac4bb6-f4cf-4431-b9ae-f357757317cd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_3e87eff4-9714-4bfd-ba7d-4d123a8ce7ed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_3e87eff4-9714-4bfd-ba7d-4d123a8ce7ed" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_8c086cb2-4544-4244-b9f3-7b7f29b35dff" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_8c086cb2-4544-4244-b9f3-7b7f29b35dff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableNet_642a4ca1-86a9-43bc-a469-b6996cfb8cc7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NotesReceivableNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_NotesReceivableNet_642a4ca1-86a9-43bc-a469-b6996cfb8cc7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_edf3fcc9-0e90-46f7-a822-4d0329cb3eac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_edf3fcc9-0e90-46f7-a822-4d0329cb3eac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_e4056c53-a23b-45ab-9641-fbcde0882db8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_Goodwill_e4056c53-a23b-45ab-9641-fbcde0882db8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets_e500b8d8-dcdd-4f93-931b-73e3ed5120ff" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssets"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_OtherAssets_e500b8d8-dcdd-4f93-931b-73e3ed5120ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_88a0d87d-8ac9-4a8b-81dc-b7971dbb7319" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_88a0d87d-8ac9-4a8b-81dc-b7971dbb7319" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_BeneficialInterestAsset_79c45ec4-65c3-41d0-ae51-8540f57c0376" xlink:href="upst-20250930.xsd#upst_BeneficialInterestAsset"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_0d245cf6-6b55-47fd-ad76-ab7737463e47" xlink:to="loc_upst_BeneficialInterestAsset_79c45ec4-65c3-41d0-ae51-8540f57c0376" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_2d0ee050-e06a-4ada-8768-07ff6b041864" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_PayableToInvestors_b242e4c4-9a1d-461e-a659-670343c02dd4" xlink:href="upst-20250930.xsd#upst_PayableToInvestors"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_2d0ee050-e06a-4ada-8768-07ff6b041864" xlink:to="loc_upst_PayableToInvestors_b242e4c4-9a1d-461e-a659-670343c02dd4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtLongtermAndShorttermCombinedAmount_a3d9d1a4-c52a-4f5e-a880-8decf6f05def" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtLongtermAndShorttermCombinedAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_2d0ee050-e06a-4ada-8768-07ff6b041864" xlink:to="loc_us-gaap_DebtLongtermAndShorttermCombinedAmount_a3d9d1a4-c52a-4f5e-a880-8decf6f05def" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_87d34c64-76b6-4829-b72e-c3cd9b696224" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesAndOtherLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_2d0ee050-e06a-4ada-8768-07ff6b041864" xlink:to="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_87d34c64-76b6-4829-b72e-c3cd9b696224" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_f68c7a99-4ee9-4cf5-92d1-0751347615e2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_2d0ee050-e06a-4ada-8768-07ff6b041864" xlink:to="loc_us-gaap_OperatingLeaseLiability_f68c7a99-4ee9-4cf5-92d1-0751347615e2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_PayableToSecuritizationNoteHoldersAtFairValue_169c9c0f-b426-4c16-8405-3cfaf9d08d67" xlink:href="upst-20250930.xsd#upst_PayableToSecuritizationNoteHoldersAtFairValue"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_2d0ee050-e06a-4ada-8768-07ff6b041864" xlink:to="loc_upst_PayableToSecuritizationNoteHoldersAtFairValue_169c9c0f-b426-4c16-8405-3cfaf9d08d67" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveIncomeLoss" xlink:type="simple" xlink:href="upst-20250930.xsd#CondensedConsolidatedStatementsofOperationsandComprehensiveIncomeLoss"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveIncomeLoss" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_2b3cbd15-f9c6-4720-bde2-fe241bcd7bec" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpense_99231c0b-168b-408d-8658-1bcb7c65eb37" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingAndMarketingExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_2b3cbd15-f9c6-4720-bde2-fe241bcd7bec" xlink:to="loc_us-gaap_SellingAndMarketingExpense_99231c0b-168b-408d-8658-1bcb7c65eb37" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_CustomerOperationsExpense_dce48b92-35f3-4a85-948d-feb561e4a090" xlink:href="upst-20250930.xsd#upst_CustomerOperationsExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_2b3cbd15-f9c6-4720-bde2-fe241bcd7bec" xlink:to="loc_upst_CustomerOperationsExpense_dce48b92-35f3-4a85-948d-feb561e4a090" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_992a5d69-6c72-4857-b49f-87cbf078b345" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_2b3cbd15-f9c6-4720-bde2-fe241bcd7bec" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_992a5d69-6c72-4857-b49f-87cbf078b345" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_61f2d581-2a30-4a3d-b57c-ff062474db74" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_2b3cbd15-f9c6-4720-bde2-fe241bcd7bec" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_61f2d581-2a30-4a3d-b57c-ff062474db74" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_1e34f053-0c37-411c-807b-08696a33f24b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_FairValueAndOtherAdjustmentsNet_169b0f64-69b2-4dfe-8469-c4e3fc6af0dd" xlink:href="upst-20250930.xsd#upst_FairValueAndOtherAdjustmentsNet"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_1e34f053-0c37-411c-807b-08696a33f24b" xlink:to="loc_upst_FairValueAndOtherAdjustmentsNet_169b0f64-69b2-4dfe-8469-c4e3fc6af0dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeOperating_176e1b19-7152-4e2e-bb37-981e7b559fb6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeOperating"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_1e34f053-0c37-411c-807b-08696a33f24b" xlink:to="loc_us-gaap_InterestIncomeOperating_176e1b19-7152-4e2e-bb37-981e7b559fb6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseOperating_4bf40fa5-fa4f-4d09-89ca-01487b9a48bd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseOperating"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_1e34f053-0c37-411c-807b-08696a33f24b" xlink:to="loc_us-gaap_InterestExpenseOperating_4bf40fa5-fa4f-4d09-89ca-01487b9a48bd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_1bbb7997-d382-4815-9f10-70319e7d9bcb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossAttributableToParent_cba2f91b-cb7f-400c-b2f7-a8ca203e178a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_1bbb7997-d382-4815-9f10-70319e7d9bcb" xlink:to="loc_us-gaap_IncomeLossAttributableToParent_cba2f91b-cb7f-400c-b2f7-a8ca203e178a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_990a951d-5f12-4b07-ba4b-6cf820924e28" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_1bbb7997-d382-4815-9f10-70319e7d9bcb" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_990a951d-5f12-4b07-ba4b-6cf820924e28" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossAttributableToParent_7bb30c84-e9d5-4c82-94e3-9813783c7e82" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_38b3eeff-33ff-49dc-9ed3-343f2411f2d2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_7bb30c84-e9d5-4c82-94e3-9813783c7e82" xlink:to="loc_us-gaap_OperatingIncomeLoss_38b3eeff-33ff-49dc-9ed3-343f2411f2d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_57e6a9fc-dcad-4df3-9118-1620b71ed787" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_7bb30c84-e9d5-4c82-94e3-9813783c7e82" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_57e6a9fc-dcad-4df3-9118-1620b71ed787" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_592ab261-1774-4910-80ca-6f0dd6c2f0cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_7bb30c84-e9d5-4c82-94e3-9813783c7e82" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_592ab261-1774-4910-80ca-6f0dd6c2f0cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_8f0b607f-99f5-4eb3-ba12-f2ca958a55e1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_aa43aea3-2fb0-40e3-9bd3-6eb635042014" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8f0b607f-99f5-4eb3-ba12-f2ca958a55e1" xlink:to="loc_us-gaap_Revenues_aa43aea3-2fb0-40e3-9bd3-6eb635042014" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_451b73ed-fa19-4d55-9148-9ab22732e959" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8f0b607f-99f5-4eb3-ba12-f2ca958a55e1" xlink:to="loc_us-gaap_OperatingExpenses_451b73ed-fa19-4d55-9148-9ab22732e959" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_975b7e1c-4085-4cff-9e66-e96840f088e6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_e81241d0-a4f0-4288-862f-54f568775ad1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Revenues_975b7e1c-4085-4cff-9e66-e96840f088e6" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_e81241d0-a4f0-4288-862f-54f568775ad1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_RevenueFromFeesNet_483144c0-df39-4aa3-a44f-59cd5b800136" xlink:href="upst-20250930.xsd#upst_RevenueFromFeesNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Revenues_975b7e1c-4085-4cff-9e66-e96840f088e6" xlink:to="loc_upst_RevenueFromFeesNet_483144c0-df39-4aa3-a44f-59cd5b800136" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="upst-20250930.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromLongTermLinesOfCredit_a73f48e9-8b73-4a2a-baa2-3fcfa1579c09" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromLongTermLinesOfCredit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_ProceedsFromLongTermLinesOfCredit_a73f48e9-8b73-4a2a-baa2-3fcfa1579c09" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromConvertibleDebt_3c35bb5d-1ef4-4074-92f8-2a0581809867" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromConvertibleDebt"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_ProceedsFromConvertibleDebt_3c35bb5d-1ef4-4074-92f8-2a0581809867" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_f8265259-17bf-41ce-9bbe-9aaa59038395" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_f8265259-17bf-41ce-9bbe-9aaa59038395" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermLinesOfCredit_24eeb322-0053-4415-b72b-53e4c5fe03ca" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermLinesOfCredit"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_RepaymentsOfLongTermLinesOfCredit_24eeb322-0053-4415-b72b-53e4c5fe03ca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfConvertibleDebt_7799f583-49b5-4ceb-bcb5-379572770198" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfConvertibleDebt"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_RepaymentsOfConvertibleDebt_7799f583-49b5-4ceb-bcb5-379572770198" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_PaymentsForCappedCalls_c2f0dbcb-7210-49b8-9b21-96f502cfdb8b" xlink:href="upst-20250930.xsd#upst_PaymentsForCappedCalls"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_upst_PaymentsForCappedCalls_c2f0dbcb-7210-49b8-9b21-96f502cfdb8b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_ProceedsFromSettlementOfCappedCalls_70b82245-3b0e-4362-ac93-3c28e606b312" xlink:href="upst-20250930.xsd#upst_ProceedsFromSettlementOfCappedCalls"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_upst_ProceedsFromSettlementOfCappedCalls_70b82245-3b0e-4362-ac93-3c28e606b312" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfAccountsReceivableSecuritization_bbd7f1da-db71-4f58-be0f-8de75b39598a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfAccountsReceivableSecuritization"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_RepaymentsOfAccountsReceivableSecuritization_bbd7f1da-db71-4f58-be0f-8de75b39598a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_RepaymentToInvestors_38f80dc6-a227-4afc-af70-4bb7f9f1fb27" xlink:href="upst-20250930.xsd#upst_RepaymentToInvestors"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_upst_RepaymentToInvestors_38f80dc6-a227-4afc-af70-4bb7f9f1fb27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans_8a9d0237-14b4-4d36-a5b5-2621b0db5ce4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans_8a9d0237-14b4-4d36-a5b5-2621b0db5ce4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_0768b2cc-000c-4619-8fda-f1003707b26c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_0768b2cc-000c-4619-8fda-f1003707b26c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_1b0ac79a-f155-4e95-9722-d7d2fad8fc03" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="12" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_ecf35b62-b019-4a4a-9850-239032437ff7" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_1b0ac79a-f155-4e95-9722-d7d2fad8fc03" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_5b9654f1-279f-4d4c-9d92-0297f0a85f31" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_2aa71521-6172-42c1-84b6-297cc50e28f1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_5b9654f1-279f-4d4c-9d92-0297f0a85f31" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_2aa71521-6172-42c1-84b6-297cc50e28f1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0bf0dd8b-9d4f-453d-ad1f-9ab23f014b6c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_5b9654f1-279f-4d4c-9d92-0297f0a85f31" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_0bf0dd8b-9d4f-453d-ad1f-9ab23f014b6c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_6cd86990-6e1f-46ce-aedb-3ad1c626abd1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_5b9654f1-279f-4d4c-9d92-0297f0a85f31" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_6cd86990-6e1f-46ce-aedb-3ad1c626abd1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPrincipalRepaymentsOnLoansAndLeasesHeldForInvestment_4aae7f20-e362-4b65-92b0-4c0f89ef0edd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromPrincipalRepaymentsOnLoansAndLeasesHeldForInvestment"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_ProceedsFromPrincipalRepaymentsOnLoansAndLeasesHeldForInvestment_4aae7f20-e362-4b65-92b0-4c0f89ef0edd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_1b4c4756-884d-4833-bb97-8de5a4d76826" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_1b4c4756-884d-4833-bb97-8de5a4d76826" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfLoansHeldForInvestment_47ec8a80-6be7-4a47-821a-b0d491ba0b5c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSaleOfLoansHeldForInvestment"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_ProceedsFromSaleOfLoansHeldForInvestment_47ec8a80-6be7-4a47-821a-b0d491ba0b5c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireLoansHeldForInvestment_118e6359-809c-4b62-bd7d-c9d8475fcc2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireLoansHeldForInvestment"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_PaymentsToAcquireLoansHeldForInvestment_118e6359-809c-4b62-bd7d-c9d8475fcc2a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_ProceedsFromBeneficialInterestAssetsInvestingActivities_05848c61-6955-4bc3-933a-c3ee423dff47" xlink:href="upst-20250930.xsd#upst_ProceedsFromBeneficialInterestAssetsInvestingActivities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_upst_ProceedsFromBeneficialInterestAssetsInvestingActivities_05848c61-6955-4bc3-933a-c3ee423dff47" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForSoftware_9884042a-0730-4e18-8903-ab2284fdd648" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForSoftware"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_PaymentsForSoftware_9884042a-0730-4e18-8903-ab2284fdd648" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromCollectionOfNotesReceivable_cd0b4db8-7387-4dc1-9031-d53b22326446" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromCollectionOfNotesReceivable"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_ProceedsFromCollectionOfNotesReceivable_cd0b4db8-7387-4dc1-9031-d53b22326446" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromCollectionOfFinanceReceivables_1b3994b7-4b3b-4f6f-9975-ef23c044745e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromCollectionOfFinanceReceivables"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_ProceedsFromCollectionOfFinanceReceivables_1b3994b7-4b3b-4f6f-9975-ef23c044745e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireFinanceReceivables_c73e94a3-31a2-4fdd-86a8-93ddd744550a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireFinanceReceivables"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_us-gaap_PaymentsToAcquireFinanceReceivables_c73e94a3-31a2-4fdd-86a8-93ddd744550a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_AcquisitionAndSettlementsOfBeneficialInterestAssets_c8fd81b2-3a99-47a0-ab8a-0832b0f09b7d" xlink:href="upst-20250930.xsd#upst_AcquisitionAndSettlementsOfBeneficialInterestAssets"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_98fb67fc-900a-4f28-8751-d360418837a7" xlink:to="loc_upst_AcquisitionAndSettlementsOfBeneficialInterestAssets_c8fd81b2-3a99-47a0-ab8a-0832b0f09b7d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b85ee39a-18f6-4e6f-9efb-34d3c22fa826" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_6956a00c-c53f-42b8-ac2b-e344cc525717" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b85ee39a-18f6-4e6f-9efb-34d3c22fa826" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_6956a00c-c53f-42b8-ac2b-e344cc525717" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCash_e356a991-8f32-4a8f-99cd-cb8b2d015f1d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCash"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b85ee39a-18f6-4e6f-9efb-34d3c22fa826" xlink:to="loc_us-gaap_RestrictedCash_e356a991-8f32-4a8f-99cd-cb8b2d015f1d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_790fce2a-ddff-4368-a6bb-2c72d4b0b16b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_NetIncomeLoss_790fce2a-ddff-4368-a6bb-2c72d4b0b16b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInFinanceReceivables_8a5fbaec-86ee-4bf2-b1a8-9ace5bca6121" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInFinanceReceivables"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_IncreaseDecreaseInFinanceReceivables_8a5fbaec-86ee-4bf2-b1a8-9ace5bca6121" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_IncreaseDecreaseInFairValueOfServicingAssets_58e70540-3a34-43d0-a716-1dab25741f37" xlink:href="upst-20250930.xsd#upst_IncreaseDecreaseInFairValueOfServicingAssets"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_IncreaseDecreaseInFairValueOfServicingAssets_58e70540-3a34-43d0-a716-1dab25741f37" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_IncreaseDecreaseInFairValueOfServicingLiabilities_877f9404-5a3f-406e-b181-0842a2118099" xlink:href="upst-20250930.xsd#upst_IncreaseDecreaseInFairValueOfServicingLiabilities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_IncreaseDecreaseInFairValueOfServicingLiabilities_877f9404-5a3f-406e-b181-0842a2118099" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_IncreaseDecreaseInFairValueOfBeneficialInterestAssets_a81b3020-abef-422d-a166-2d57ca20ef15" xlink:href="upst-20250930.xsd#upst_IncreaseDecreaseInFairValueOfBeneficialInterestAssets"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_IncreaseDecreaseInFairValueOfBeneficialInterestAssets_a81b3020-abef-422d-a166-2d57ca20ef15" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_IncreaseDecreaseInFairValueOfBeneficialInterestLiabilities_e13b86fe-e67b-4473-80bf-bac9519c33ac" xlink:href="upst-20250930.xsd#upst_IncreaseDecreaseInFairValueOfBeneficialInterestLiabilities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_IncreaseDecreaseInFairValueOfBeneficialInterestLiabilities_e13b86fe-e67b-4473-80bf-bac9519c33ac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherFinancialInstrumentsUsedInOperatingActivities_846e13ce-233a-4009-83b7-7472b2f43eda" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherFinancialInstrumentsUsedInOperatingActivities"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherFinancialInstrumentsUsedInOperatingActivities_846e13ce-233a-4009-83b7-7472b2f43eda" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_500c9864-353f-4f08-a7da-640e9a4775ba" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_ShareBasedCompensation_500c9864-353f-4f08-a7da-640e9a4775ba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_GainLossOnLoanServicingRightsAndSaleOfNoncontrollingInterestsNet_dcb71d77-d178-4c7a-aeac-5237755e4b5a" xlink:href="upst-20250930.xsd#upst_GainLossOnLoanServicingRightsAndSaleOfNoncontrollingInterestsNet"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_GainLossOnLoanServicingRightsAndSaleOfNoncontrollingInterestsNet_dcb71d77-d178-4c7a-aeac-5237755e4b5a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_e0cc53f4-f0ea-4969-a5c7-2db88e033648" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_e0cc53f4-f0ea-4969-a5c7-2db88e033648" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_dac44dbb-d5b3-4440-a84c-79f52ac97662" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_dac44dbb-d5b3-4440-a84c-79f52ac97662" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_AmortizationOfLoanPremium_6546b9c4-9ac5-4b66-a587-a56095f84ab5" xlink:href="upst-20250930.xsd#upst_AmortizationOfLoanPremium"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_AmortizationOfLoanPremium_6546b9c4-9ac5-4b66-a587-a56095f84ab5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaidInKindInterest_7dac4111-30c9-4fb8-a01f-c7df08f8633d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaidInKindInterest"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_PaidInKindInterest_7dac4111-30c9-4fb8-a01f-c7df08f8633d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToPurchaseLoansHeldForSale_53e041d1-7ba7-4504-86e3-4b16ad7d34e0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToPurchaseLoansHeldForSale"/>
    <link:calculationArc order="14" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_PaymentsToPurchaseLoansHeldForSale_53e041d1-7ba7-4504-86e3-4b16ad7d34e0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfLoansHeldForSale_52e1f194-6ddd-4b39-b83e-1c700f447247" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSaleOfLoansHeldForSale"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_ProceedsFromSaleOfLoansHeldForSale_52e1f194-6ddd-4b39-b83e-1c700f447247" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromCollectionOfLoansHeldForSale_6e32952f-53c5-4539-8494-1b3c08f48c1c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromCollectionOfLoansHeldForSale"/>
    <link:calculationArc order="16" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_ProceedsFromCollectionOfLoansHeldForSale_6e32952f-53c5-4539-8494-1b3c08f48c1c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSecuritizationsOfLoansHeldForSale_7cad9d7a-d564-4b93-b2df-7769c8f550e6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSecuritizationsOfLoansHeldForSale"/>
    <link:calculationArc order="17" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_ProceedsFromSecuritizationsOfLoansHeldForSale_7cad9d7a-d564-4b93-b2df-7769c8f550e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_PaymentsOnBeneficialInterestLiabilities_f8718992-7bb4-4cb6-a0d4-8efaa5733cc9" xlink:href="upst-20250930.xsd#upst_PaymentsOnBeneficialInterestLiabilities"/>
    <link:calculationArc order="18" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_PaymentsOnBeneficialInterestLiabilities_f8718992-7bb4-4cb6-a0d4-8efaa5733cc9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_ProceedsFromBeneficialInterestAssetsOperatingActivities_18012746-4d95-4024-b301-bd8a8ffb6014" xlink:href="upst-20250930.xsd#upst_ProceedsFromBeneficialInterestAssetsOperatingActivities"/>
    <link:calculationArc order="19" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_ProceedsFromBeneficialInterestAssetsOperatingActivities_18012746-4d95-4024-b301-bd8a8ffb6014" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_PaymentsOnBeneficialInterestAssetsOperatingActivities_9ee594af-a2e9-4e83-84d4-59daeba79320" xlink:href="upst-20250930.xsd#upst_PaymentsOnBeneficialInterestAssetsOperatingActivities"/>
    <link:calculationArc order="20" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_PaymentsOnBeneficialInterestAssetsOperatingActivities_9ee594af-a2e9-4e83-84d4-59daeba79320" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_af3396ee-ad67-42f1-a598-ffeadca299a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="21" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_af3396ee-ad67-42f1-a598-ffeadca299a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_IncreaseDecreaseInOperatingLeaseLiabilityAndRightOfUseAsset_6d76e866-9c70-4705-ab8a-cfe3960157c3" xlink:href="upst-20250930.xsd#upst_IncreaseDecreaseInOperatingLeaseLiabilityAndRightOfUseAsset"/>
    <link:calculationArc order="22" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_upst_IncreaseDecreaseInOperatingLeaseLiabilityAndRightOfUseAsset_6d76e866-9c70-4705-ab8a-cfe3960157c3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities_87204169-a991-4b11-8d84-cf653b9797ce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities"/>
    <link:calculationArc order="23" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a483e244-6eac-4a49-b697-697cb29cf8e1" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities_87204169-a991-4b11-8d84-cf653b9797ce" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/RevenueScheduleofComponentsofInterestIncomeandFairValueAdjustmentsNetDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#RevenueScheduleofComponentsofInterestIncomeandFairValueAdjustmentsNetDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/RevenueScheduleofComponentsofInterestIncomeandFairValueAdjustmentsNetDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_upst_InterestIncomeAndFairValueAdjustmentNet_8f4d1e88-1760-41ee-8eb9-e109e7f9cc08" xlink:href="upst-20250930.xsd#upst_InterestIncomeAndFairValueAdjustmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseOperating_273af605-03ab-40c8-895a-d0625c26a032" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseOperating"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_InterestIncomeAndFairValueAdjustmentNet_8f4d1e88-1760-41ee-8eb9-e109e7f9cc08" xlink:to="loc_us-gaap_InterestExpenseOperating_273af605-03ab-40c8-895a-d0625c26a032" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_FairValueAndOtherAdjustmentsNet_13c198de-a1b0-4722-a341-3c616d0a75b2" xlink:href="upst-20250930.xsd#upst_FairValueAndOtherAdjustmentsNet"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_InterestIncomeAndFairValueAdjustmentNet_8f4d1e88-1760-41ee-8eb9-e109e7f9cc08" xlink:to="loc_upst_FairValueAndOtherAdjustmentsNet_13c198de-a1b0-4722-a341-3c616d0a75b2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeOperating_25b3a553-86e3-4da7-95e0-bb6d3b57ddd7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeOperating"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_InterestIncomeAndFairValueAdjustmentNet_8f4d1e88-1760-41ee-8eb9-e109e7f9cc08" xlink:to="loc_us-gaap_InterestIncomeOperating_25b3a553-86e3-4da7-95e0-bb6d3b57ddd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_FairValueAndOtherAdjustmentsNet_530b6cc8-2029-405e-b0ef-b81a911e1e65" xlink:href="upst-20250930.xsd#upst_FairValueAndOtherAdjustmentsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_UnrealizedGainLossChargeOffsAndOtherFairValueAdjustmentsNet_a0a9b577-0ae3-462b-8d66-61bf3517e5c9" xlink:href="upst-20250930.xsd#upst_UnrealizedGainLossChargeOffsAndOtherFairValueAdjustmentsNet"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_FairValueAndOtherAdjustmentsNet_530b6cc8-2029-405e-b0ef-b81a911e1e65" xlink:to="loc_upst_UnrealizedGainLossChargeOffsAndOtherFairValueAdjustmentsNet_a0a9b577-0ae3-462b-8d66-61bf3517e5c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_RealizedGainLossOnTransferOfLoansNet_15f83a3c-7a1d-4c8f-abc4-359bef5a4f52" xlink:href="upst-20250930.xsd#upst_RealizedGainLossOnTransferOfLoansNet"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_FairValueAndOtherAdjustmentsNet_530b6cc8-2029-405e-b0ef-b81a911e1e65" xlink:to="loc_upst_RealizedGainLossOnTransferOfLoansNet_15f83a3c-7a1d-4c8f-abc4-359bef5a4f52" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_GainLossOnBeneficialInterests_1445a289-9cf6-4c9e-8b5b-bb2df71b8800" xlink:href="upst-20250930.xsd#upst_GainLossOnBeneficialInterests"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_FairValueAndOtherAdjustmentsNet_530b6cc8-2029-405e-b0ef-b81a911e1e65" xlink:to="loc_upst_GainLossOnBeneficialInterests_1445a289-9cf6-4c9e-8b5b-bb2df71b8800" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/FairValueMeasurementScheduleofAssetsandLiabilitiesMeasuredatFairValueDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#FairValueMeasurementScheduleofAssetsandLiabilitiesMeasuredatFairValueDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/FairValueMeasurementScheduleofAssetsandLiabilitiesMeasuredatFairValueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_b9442e17-e11d-4572-bddb-2eb44b57c891" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ServicingLiabilityAtFairValueAmount_233bf60b-7ee5-48dd-a20d-d7614d0e44d3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ServicingLiabilityAtFairValueAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_b9442e17-e11d-4572-bddb-2eb44b57c891" xlink:to="loc_us-gaap_ServicingLiabilityAtFairValueAmount_233bf60b-7ee5-48dd-a20d-d7614d0e44d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_BeneficialInterestLiabilities_b41987e4-f16d-45d1-8302-1775058fdd56" xlink:href="upst-20250930.xsd#upst_BeneficialInterestLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_b9442e17-e11d-4572-bddb-2eb44b57c891" xlink:to="loc_upst_BeneficialInterestLiabilities_b41987e4-f16d-45d1-8302-1775058fdd56" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_TrailingFeeLiabilitiesFairValueDisclosure_761e1d53-4217-46f8-b624-2da9d0f5f320" xlink:href="upst-20250930.xsd#upst_TrailingFeeLiabilitiesFairValueDisclosure"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_b9442e17-e11d-4572-bddb-2eb44b57c891" xlink:to="loc_upst_TrailingFeeLiabilitiesFairValueDisclosure_761e1d53-4217-46f8-b624-2da9d0f5f320" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_PayableToSecuritizationNoteHoldersAtFairValue_116dae95-0e7a-4cf0-9068-6b027935ed49" xlink:href="upst-20250930.xsd#upst_PayableToSecuritizationNoteHoldersAtFairValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_b9442e17-e11d-4572-bddb-2eb44b57c891" xlink:to="loc_upst_PayableToSecuritizationNoteHoldersAtFairValue_116dae95-0e7a-4cf0-9068-6b027935ed49" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansReceivableFairValueDisclosure_8aecd4af-6f9d-41ae-9d1d-4e9dfd0f495a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LoansReceivableFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:to="loc_us-gaap_LoansReceivableFairValueDisclosure_8aecd4af-6f9d-41ae-9d1d-4e9dfd0f495a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableFairValueDisclosure_a5a5e7da-ad24-4895-be40-648a80e38f27" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NotesReceivableFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:to="loc_us-gaap_NotesReceivableFairValueDisclosure_a5a5e7da-ad24-4895-be40-648a80e38f27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ServicingAssetAtFairValueAmount_abfb199b-9dc5-4943-a164-6b38e61e5944" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ServicingAssetAtFairValueAmount"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:to="loc_us-gaap_ServicingAssetAtFairValueAmount_abfb199b-9dc5-4943-a164-6b38e61e5944" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateDerivativeAssetsAtFairValue_c8272bde-6224-443f-9a2d-a868e7461cf0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestRateDerivativeAssetsAtFairValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:to="loc_us-gaap_InterestRateDerivativeAssetsAtFairValue_c8272bde-6224-443f-9a2d-a868e7461cf0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LineOfCreditReceivableFairValueDisclosure_d4a46747-0e1d-4429-958b-e00779bcba24" xlink:href="upst-20250930.xsd#upst_LineOfCreditReceivableFairValueDisclosure"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:to="loc_upst_LineOfCreditReceivableFairValueDisclosure_d4a46747-0e1d-4429-958b-e00779bcba24" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_BeneficialInterestAssetFairValue_151f18d5-c76d-420f-995c-4361987415ce" xlink:href="upst-20250930.xsd#upst_BeneficialInterestAssetFairValue"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_4a6265a0-e161-461b-9343-2a8e7c8c91f1" xlink:to="loc_upst_BeneficialInterestAssetFairValue_151f18d5-c76d-420f-995c-4361987415ce" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/FairValueMeasurementScheduleofFairValueofClassesofLoansHeldbytheCompanyDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#FairValueMeasurementScheduleofFairValueofClassesofLoansHeldbytheCompanyDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/FairValueMeasurementScheduleofFairValueofClassesofLoansHeldbytheCompanyDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansReceivableFairValueDisclosure_548cf99c-4ff4-4eba-ab92-fdfac52bd97e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LoansReceivableFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansHeldForSaleFairValueDisclosure_1c566260-2da7-470c-8fd9-80983ece5181" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LoansHeldForSaleFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansReceivableFairValueDisclosure_548cf99c-4ff4-4eba-ab92-fdfac52bd97e" xlink:to="loc_us-gaap_LoansHeldForSaleFairValueDisclosure_1c566260-2da7-470c-8fd9-80983ece5181" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LoansHeldInConsolidatedSecuritizationFairValueDisclosure_d9d2893c-dc5e-4cc2-af77-e9df59c67677" xlink:href="upst-20250930.xsd#upst_LoansHeldInConsolidatedSecuritizationFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansReceivableFairValueDisclosure_548cf99c-4ff4-4eba-ab92-fdfac52bd97e" xlink:to="loc_upst_LoansHeldInConsolidatedSecuritizationFairValueDisclosure_d9d2893c-dc5e-4cc2-af77-e9df59c67677" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LoansHeldForInvestmentFairValueDisclosure_04614506-75d4-4b05-bb65-5f15d3cac12e" xlink:href="upst-20250930.xsd#upst_LoansHeldForInvestmentFairValueDisclosure"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansReceivableFairValueDisclosure_548cf99c-4ff4-4eba-ab92-fdfac52bd97e" xlink:to="loc_upst_LoansHeldForInvestmentFairValueDisclosure_04614506-75d4-4b05-bb65-5f15d3cac12e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/FairValueMeasurementScheduleofAggregateFairValueandPrincipalOutstandingofAllLoansAndLoans90DaysorMorePastDueDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#FairValueMeasurementScheduleofAggregateFairValueandPrincipalOutstandingofAllLoansAndLoans90DaysorMorePastDueDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/FairValueMeasurementScheduleofAggregateFairValueandPrincipalOutstandingofAllLoansAndLoans90DaysorMorePastDueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableNet_6a2ceec7-d853-444e-a896-ce5f3ac73df3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NotesReceivableNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesReceivableGross_30ee9d2a-6a98-44e0-af4d-d3eeea2e6cbe" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NotesReceivableGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NotesReceivableNet_6a2ceec7-d853-444e-a896-ce5f3ac73df3" xlink:to="loc_us-gaap_NotesReceivableGross_30ee9d2a-6a98-44e0-af4d-d3eeea2e6cbe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_7040607f-bd32-404c-9035-9618eeb183ac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinancingReceivableAllowanceForCreditLosses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NotesReceivableNet_6a2ceec7-d853-444e-a896-ce5f3ac73df3" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLosses_7040607f-bd32-404c-9035-9618eeb183ac" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/GoodwillandIntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#GoodwillandIntangibleAssetsScheduleofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/GoodwillandIntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_5d509d4a-1081-4c8a-b06b-f44daee5e285" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_88bc1f48-3083-4400-bb51-edb61868e08e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_5d509d4a-1081-4c8a-b06b-f44daee5e285" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_88bc1f48-3083-4400-bb51-edb61868e08e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_8347e68b-373a-4a65-90f3-eaf7928ab3b0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_5d509d4a-1081-4c8a-b06b-f44daee5e285" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_8347e68b-373a-4a65-90f3-eaf7928ab3b0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/GoodwillandIntangibleAssetsScheduleofExpectedFutureAmortizationExpenseDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#GoodwillandIntangibleAssetsScheduleofExpectedFutureAmortizationExpenseDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/GoodwillandIntangibleAssetsScheduleofExpectedFutureAmortizationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_3de97c66-927d-439c-9a3c-7b39dcebfa0d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_3de97c66-927d-439c-9a3c-7b39dcebfa0d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_d9f1a72b-46d8-4bd5-94cf-d116b5f9c097" xlink:href="upst-20250930.xsd#upst_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:to="loc_upst_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_d9f1a72b-46d8-4bd5-94cf-d116b5f9c097" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_a669efd4-9b5e-40ec-9d5f-7d11ac1fc1a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_a669efd4-9b5e-40ec-9d5f-7d11ac1fc1a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_0b0a930b-ce29-4b19-a3d0-0da77496bd20" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_0b0a930b-ce29-4b19-a3d0-0da77496bd20" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_26f1fce2-b499-4126-b99f-d0cde5dd1eb3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_26f1fce2-b499-4126-b99f-d0cde5dd1eb3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_82d9ff9b-9d3b-4a57-93f1-af093803fa70" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_98aa83ce-b49f-4ee6-b379-16eaa7a749f1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_82d9ff9b-9d3b-4a57-93f1-af093803fa70" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/BalanceSheetComponentsScheduleofOtherAssetsDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#BalanceSheetComponentsScheduleofOtherAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/BalanceSheetComponentsScheduleofOtherAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsMiscellaneous_8dfa5ae5-ecc9-4f6b-8b26-ead91c6b04f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsMiscellaneous"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_OtherAssetsMiscellaneous_8dfa5ae5-ecc9-4f6b-8b26-ead91c6b04f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseCurrentAndNoncurrent_5731fb83-846a-4a3f-87ab-6317c78b2ef4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrepaidExpenseCurrentAndNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_PrepaidExpenseCurrentAndNoncurrent_5731fb83-846a-4a3f-87ab-6317c78b2ef4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAssets_d990a938-93fa-4b00-8c7b-56998224bfd4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepositsAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_DepositsAssets_d990a938-93fa-4b00-8c7b-56998224bfd4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ServicingAssetAtFairValueAmount_8e6eda87-e7b6-4e1a-9a0f-0487d325438e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ServicingAssetAtFairValueAmount"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_ServicingAssetAtFairValueAmount_8e6eda87-e7b6-4e1a-9a0f-0487d325438e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivables_1d3d2b63-f0e4-4624-a5a0-dc0c5857505f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherReceivables"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_OtherReceivables_1d3d2b63-f0e4-4624-a5a0-dc0c5857505f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedFeesAndOtherRevenueReceivable_27c38172-d699-46f1-bed9-3c4d81a7b00c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedFeesAndOtherRevenueReceivable"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_AccruedFeesAndOtherRevenueReceivable_27c38172-d699-46f1-bed9-3c4d81a7b00c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6780a12b-f43f-4fe4-9685-5be5c0eb7e8f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_6780a12b-f43f-4fe4-9685-5be5c0eb7e8f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LineOfCreditReceivableFairValueDisclosure_604316af-dcf1-4d33-ada9-8c2162496a60" xlink:href="upst-20250930.xsd#upst_LineOfCreditReceivableFairValueDisclosure"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssets_2824854e-eb18-46f2-a644-43d31676ab58" xlink:to="loc_upst_LineOfCreditReceivableFairValueDisclosure_604316af-dcf1-4d33-ada9-8c2162496a60" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/BalanceSheetComponentsScheduleofPropertyEquipmentandSoftwareDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#BalanceSheetComponentsScheduleofPropertyEquipmentandSoftwareDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/BalanceSheetComponentsScheduleofPropertyEquipmentandSoftwareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_8a0ae65e-b2fd-491e-8d89-debcc38cfe01" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_7971c532-2203-4654-a02a-5189aaa637e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_8a0ae65e-b2fd-491e-8d89-debcc38cfe01" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_7971c532-2203-4654-a02a-5189aaa637e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_2a1a62de-6cf9-4b8b-a274-823f4b7f2c5b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_8a0ae65e-b2fd-491e-8d89-debcc38cfe01" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_2a1a62de-6cf9-4b8b-a274-823f4b7f2c5b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/BalanceSheetComponentsScheduleofAccruedExpensesandOtherLiabilitiesDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#BalanceSheetComponentsScheduleofAccruedExpensesandOtherLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/BalanceSheetComponentsScheduleofAccruedExpensesandOtherLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesAndOtherLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrent_64954521-ea93-49d0-8356-863c86bcbff4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrentAndNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrentAndNoncurrent_64954521-ea93-49d0-8356-863c86bcbff4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrentAndNoncurrent_47d73dbc-b867-4e59-bdda-4c6348e180bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrentAndNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_us-gaap_AccountsPayableCurrentAndNoncurrent_47d73dbc-b867-4e59-bdda-4c6348e180bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrentAndNoncurrent_8b945410-384e-4a12-86d3-32c5296b634f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrentAndNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrentAndNoncurrent_8b945410-384e-4a12-86d3-32c5296b634f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ServicingLiabilityAtFairValueAmount_3c3f03b8-442d-4a87-bffa-4e8e18469b35" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ServicingLiabilityAtFairValueAmount"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_us-gaap_ServicingLiabilityAtFairValueAmount_3c3f03b8-442d-4a87-bffa-4e8e18469b35" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_TrailingFeeLiabilityAtFairValueAmount_0e98c75a-ee47-4635-9d0b-fd2751895475" xlink:href="upst-20250930.xsd#upst_TrailingFeeLiabilityAtFairValueAmount"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_upst_TrailingFeeLiabilityAtFairValueAmount_0e98c75a-ee47-4635-9d0b-fd2751895475" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilities_33f6e817-be29-4ec9-b1ac-361942e69b11" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_us-gaap_OtherLiabilities_33f6e817-be29-4ec9-b1ac-361942e69b11" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BeneficialInterest_be782947-17f2-4847-883b-a0ffbd678d90" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BeneficialInterest"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilities_a46523b4-96c7-4718-ae54-ecd0eaf3199b" xlink:to="loc_us-gaap_BeneficialInterest_be782947-17f2-4847-883b-a0ffbd678d90" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/BorrowingsScheduleofAggregatePrincipalOutstandingofallLoansDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#BorrowingsScheduleofAggregatePrincipalOutstandingofallLoansDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/BorrowingsScheduleofAggregatePrincipalOutstandingofallLoansDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtLongtermAndShorttermCombinedAmount_4bb938db-6131-48b3-b1a0-2f1e09be6075" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtLongtermAndShorttermCombinedAmount"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtGross_ce4a991a-a6db-4eb0-a420-f40154053320" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtLongtermAndShorttermCombinedAmount_4bb938db-6131-48b3-b1a0-2f1e09be6075" xlink:to="loc_upst_LongTermAndShortTermDebtGross_ce4a991a-a6db-4eb0-a420-f40154053320" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_70cdec84-75c3-49fd-9a77-059d3151523a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentUnamortizedDiscount"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtLongtermAndShorttermCombinedAmount_4bb938db-6131-48b3-b1a0-2f1e09be6075" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_70cdec84-75c3-49fd-9a77-059d3151523a" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/BorrowingsScheduleofMaturitiesofAllBorrowingsDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#BorrowingsScheduleofMaturitiesofAllBorrowingsDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/BorrowingsScheduleofMaturitiesofAllBorrowingsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityYearFour_7f308bdb-85a6-4479-8625-bc4dd1054010" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityYearFour"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityYearFour_7f308bdb-85a6-4479-8625-bc4dd1054010" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityYearFive_ec27cff0-6f70-465b-9bd0-c4e9ee57e4c4" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityYearFive"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityYearFive_ec27cff0-6f70-465b-9bd0-c4e9ee57e4c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityAfterYearFive_ca2aae55-cf8e-475a-b241-b7769f04cbb0" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityAfterYearFive"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityAfterYearFive_ca2aae55-cf8e-475a-b241-b7769f04cbb0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityYearTwo_818df4d2-e456-44fc-a616-63a241201d96" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityYearTwo"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityYearTwo_818df4d2-e456-44fc-a616-63a241201d96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityYearOne_cb9cc0d0-505a-47a3-b6d8-0442b8ede2ab" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityYearOne"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityYearOne_cb9cc0d0-505a-47a3-b6d8-0442b8ede2ab" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityYearThree_2720ea29-3658-4fcf-b93a-ae9ef2c5325c" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityYearThree"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityYearThree_2720ea29-3658-4fcf-b93a-ae9ef2c5325c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_LongTermAndShortTermDebtMaturityRemainderOfFiscalYear_06ed8576-f8a3-4e78-85fb-425c2708f998" xlink:href="upst-20250930.xsd#upst_LongTermAndShortTermDebtMaturityRemainderOfFiscalYear"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_LongTermAndShortTermDebtGross_2dc60fda-e441-44bb-8a90-8cc1b9250b35" xlink:to="loc_upst_LongTermAndShortTermDebtMaturityRemainderOfFiscalYear_06ed8576-f8a3-4e78-85fb-425c2708f998" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/BorrowingsConvertibleSeniorNotesDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#BorrowingsConvertibleSeniorNotesDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/BorrowingsConvertibleSeniorNotesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_9a2f4e18-a299-40e7-b536-fd2829023894" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_c1b7f236-7011-4314-9b09-fc0bf2f8440c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_9a2f4e18-a299-40e7-b536-fd2829023894" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_c1b7f236-7011-4314-9b09-fc0bf2f8440c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_c8269208-3477-414f-88a8-90ebca92e4aa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentUnamortizedDiscount"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_9a2f4e18-a299-40e7-b536-fd2829023894" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_c8269208-3477-414f-88a8-90ebca92e4aa" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/LeasesScheduleofFutureMinimumLeasePaymentsDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#LeasesScheduleofFutureMinimumLeasePaymentsDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/LeasesScheduleofFutureMinimumLeasePaymentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_588b7f50-75c3-4c99-ab63-6a614f9e0ddb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_c76d1999-08b8-4e7c-8e0a-49ebb71f5c3f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_588b7f50-75c3-4c99-ab63-6a614f9e0ddb" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_c76d1999-08b8-4e7c-8e0a-49ebb71f5c3f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_435f1e24-eb34-4769-938e-4a3f83f437f6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_588b7f50-75c3-4c99-ab63-6a614f9e0ddb" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_435f1e24-eb34-4769-938e-4a3f83f437f6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_0b944010-f961-4fa8-9739-858ef79a6233" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_588b7f50-75c3-4c99-ab63-6a614f9e0ddb" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_0b944010-f961-4fa8-9739-858ef79a6233" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_15c0130a-c45c-4fde-a544-6e14875edb96" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_588b7f50-75c3-4c99-ab63-6a614f9e0ddb" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_15c0130a-c45c-4fde-a544-6e14875edb96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_1687a79f-c698-4a5d-bf8d-991e1eaa4844" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_588b7f50-75c3-4c99-ab63-6a614f9e0ddb" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_1687a79f-c698-4a5d-bf8d-991e1eaa4844" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/LeasesScheduleofFutureMinimumLeasePaymentsDetails_1" xlink:type="simple" xlink:href="upst-20250930.xsd#LeasesScheduleofFutureMinimumLeasePaymentsDetails_1"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/LeasesScheduleofFutureMinimumLeasePaymentsDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_7b76aaa0-a753-4d6f-ae7b-57ce0dc01c2d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_9922514e-d324-4666-abf4-c2254f719bc5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_7b76aaa0-a753-4d6f-ae7b-57ce0dc01c2d" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_9922514e-d324-4666-abf4-c2254f719bc5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_63ea9f41-08ec-4b86-8540-615303cae760" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_7b76aaa0-a753-4d6f-ae7b-57ce0dc01c2d" xlink:to="loc_us-gaap_OperatingLeaseLiability_63ea9f41-08ec-4b86-8540-615303cae760" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/NetIncomeLossPerShareScheduleofNetLossPerShareDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#NetIncomeLossPerShareScheduleofNetLossPerShareDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/NetIncomeLossPerShareScheduleofNetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_9ce7e33c-a1d1-4034-98d0-6f6948c898ab" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_e0765a76-3434-48ef-9b7f-129ba5935946" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_9ce7e33c-a1d1-4034-98d0-6f6948c898ab" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_e0765a76-3434-48ef-9b7f-129ba5935946" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_e310fa03-49c3-4c97-ba5a-77ab15e27822" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_9ce7e33c-a1d1-4034-98d0-6f6948c898ab" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_e310fa03-49c3-4c97-ba5a-77ab15e27822" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_e8ad39a0-e7cd-4595-a529-2624813932a3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_6f75402c-cd6b-4550-b148-01301ba6210d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_e8ad39a0-e7cd-4595-a529-2624813932a3" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_6f75402c-cd6b-4550-b148-01301ba6210d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_2906c8b2-affa-457b-a5e7-c392cf1dd4c4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_e8ad39a0-e7cd-4595-a529-2624813932a3" xlink:to="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_2906c8b2-affa-457b-a5e7-c392cf1dd4c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_70f0d102-f944-4e70-bbf2-3d9e97b13d5a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_239f3311-bf7d-4fa4-abe9-1039ff88159e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_70f0d102-f944-4e70-bbf2-3d9e97b13d5a" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_239f3311-bf7d-4fa4-abe9-1039ff88159e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_DilutiveEffectOfConvertibleSeniorNotesNet_f89d0088-369d-4f9e-8367-ccb595e107ed" xlink:href="upst-20250930.xsd#upst_DilutiveEffectOfConvertibleSeniorNotesNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_70f0d102-f944-4e70-bbf2-3d9e97b13d5a" xlink:to="loc_upst_DilutiveEffectOfConvertibleSeniorNotesNet_f89d0088-369d-4f9e-8367-ccb595e107ed" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/SegmentInformationContributionProfitfortheCompanysUnsecuredLendingSegmentDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#SegmentInformationContributionProfitfortheCompanysUnsecuredLendingSegmentDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/SegmentInformationContributionProfitfortheCompanysUnsecuredLendingSegmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_upst_ContributionProfit_0f66eeaa-031e-43c7-8eed-ae301e244190" xlink:href="upst-20250930.xsd#upst_ContributionProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_BorrowerVerificationAndServicingCosts_627d92e9-71e1-4ea8-b484-1a4dd481d636" xlink:href="upst-20250930.xsd#upst_BorrowerVerificationAndServicingCosts"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_ContributionProfit_0f66eeaa-031e-43c7-8eed-ae301e244190" xlink:to="loc_upst_BorrowerVerificationAndServicingCosts_627d92e9-71e1-4ea8-b484-1a4dd481d636" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_RevenueFromFeesNet_9bc99448-37b2-46ff-99fa-1c95b68ec1b3" xlink:href="upst-20250930.xsd#upst_RevenueFromFeesNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_ContributionProfit_0f66eeaa-031e-43c7-8eed-ae301e244190" xlink:to="loc_upst_RevenueFromFeesNet_9bc99448-37b2-46ff-99fa-1c95b68ec1b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_BorrowerAcquisitionCosts_ad997c44-81b9-4157-a220-d40d4bc693d0" xlink:href="upst-20250930.xsd#upst_BorrowerAcquisitionCosts"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_upst_ContributionProfit_0f66eeaa-031e-43c7-8eed-ae301e244190" xlink:to="loc_upst_BorrowerAcquisitionCosts_ad997c44-81b9-4157-a220-d40d4bc693d0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.upstartholdings.com/role/SegmentInformationReconciliationofTotalContributionProfittoNetLossBeforeIncomeTaxesDetails" xlink:type="simple" xlink:href="upst-20250930.xsd#SegmentInformationReconciliationofTotalContributionProfittoNetLossBeforeIncomeTaxesDetails"/>
  <link:calculationLink xlink:role="http://www.upstartholdings.com/role/SegmentInformationReconciliationofTotalContributionProfittoNetLossBeforeIncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_7c0fbb32-9bb7-4442-bbf3-3134b5800edb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_7c0fbb32-9bb7-4442-bbf3-3134b5800edb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_5f988bcb-e3fd-4cbd-a1a4-8c0cfd40d3d6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_5f988bcb-e3fd-4cbd-a1a4-8c0cfd40d3d6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_ContributionProfitOther_efc1ca07-4dde-47fd-9f2f-920ba5fecdb9" xlink:href="upst-20250930.xsd#upst_ContributionProfitOther"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_upst_ContributionProfitOther_efc1ca07-4dde-47fd-9f2f-920ba5fecdb9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_6c974b38-b4f3-4547-bd81-dc462e98b09c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_6c974b38-b4f3-4547-bd81-dc462e98b09c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_a9458fe0-a763-4da3-b6d3-b20480844994" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_a9458fe0-a763-4da3-b6d3-b20480844994" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpense_7177fa30-81e0-4bfc-8726-e2f202f59aea" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingAndMarketingExpense"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_us-gaap_SellingAndMarketingExpense_7177fa30-81e0-4bfc-8726-e2f202f59aea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_ContributionProfit_a8c2c431-a7ba-4f81-9099-623196a94b9b" xlink:href="upst-20250930.xsd#upst_ContributionProfit"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_upst_ContributionProfit_a8c2c431-a7ba-4f81-9099-623196a94b9b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_upst_CustomerOperationsExpense_6e3d5a92-bc03-48c3-97c8-3f09d9860ca1" xlink:href="upst-20250930.xsd#upst_CustomerOperationsExpense"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_upst_CustomerOperationsExpense_6e3d5a92-bc03-48c3-97c8-3f09d9860ca1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_f197e603-d239-48bc-818b-f68d2794ce10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossAttributableToParent_4c341514-55fb-434a-af14-463de5a1023f" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_f197e603-d239-48bc-818b-f68d2794ce10" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
